Famous People with Klinefelter Syndrome | Personalities to Know

famous people with klinefelter syndrome

An accidental inherent abnormality after conception causes Klinefelter Syndrome. This genetic disorder causes an infant to be born having an additional copy of the X chromosome, meaning, therefore, he is XXY instead of XY. Dr. Klinefelter, the famous endocrinologist who worked at Boston’s Massachusetts General Hospital, initially reported this disease in 1942. It primarily affects boys, and since it is hard to make a diagnosis in childhood, boys are typically diagnosed in adolescence. Despite being a disorder that affects more than 600 men, most people, including many of those with it, do not know of it. 

Regretfully, there is no treatment for this illness. treatment for this chromosomal abnormality frequently for related health issues. Replacement therapy for testosterone is the other treatment option. For youngsters to develop their speech properly, doctors also advise speech and language therapy.

Who are the famous people with Klinefelter Syndrome?

Let’s take a look at a few of the famous people with Klinefelter Syndrome who have made their diagnoses public, as well as those who are strongly suspected of having it:

1. Charles Barkley

Charles Barkley

An American former basketball professional competitor, Charles played for the NBA’s Philadelphia 76ers, Phoenix Suns, as well as Houston Rockets. He provides analysis for the NBA on TNT. Though he is one of the most amazing and famous people with Klinefelter Syndrome, Barkley overcame the disability to become one of the greatest of all time in basketball. He has won two MVP awards, been named to the NBA All-Star team ten times, and won gold at the Olympics twice. The Naismith Memorial Basketball Hall of Fame counts him among its members.

2. Anthony Robbins

famous people with klinefelter syndrome

In 1983, the Robbins Research Institute was established by Tony Robbins, an American writer, philanthropist, activist and motivational speaker. He persisted after receiving a diagnosis of Klinefelter syndrome as a youngster; he was raised in Los Angeles in 1960. Today, he is known as one of the most famous people with Klinefelter Syndrome. He helped people face their fears and phobias by studying personal growth ideas, especially those of John Grinder and Richard Bandler, who co-created NLP. Magazines such as Fortune, The New York Times, and The Wall Street Journal have covered Robbins, who has authored multiple book as well as created films.

Education, impoverishment, and disaster assistance are some of the causes to which he has given millions of dollars as a philanthropist. In addition, the Anthony Robbins Foundation, which he established, gives money to groups that help individuals realize their greatest potential. The Horatio Alger Award went to Robbins for his perseverance in the face of hardship, and he is now an affiliate of multiple boards of directors. Sage Robbins is his wife, and the couple has two kids. 

3. Floyd Mayweather Jr.

Floyd Mayweather Jr.

Famous boxer Floyd Mayweather Jr. retired after 50 fights victorious and is generally regarded as one of the sport’s all-time greats. Even though Mayweather received a childhood diagnosis of Klinefelter syndrome (Klinefelter Syndrome), he never let it impact his ability in the ring.

Mayweather has not yet addressed his Klinefelter Syndrome diagnosis in a public setting, although many believe it played a role in his mild gynecomastia along with low testosterone levels. Having said that, Mayweather has said that he has been one of the most famous people with Klinefelter Syndrome and his Klinefelter Syndrome has altered his outlook on life and made him a stronger, more focused fighter. 

4. Michael Phelps

famous people with klinefelter syndrome

Michael, a former competitive swimmer from the United States, is generally considered to be among the all-time greats. His 28 medals make him the most successful Olympian in history. When he was 16 years old, he received the diagnosis of Klinefelter Syndrome. However, it did not stop him from reaching his maximum potential. In total, he won 23 Olympic gold medals, eight of which came at the 2008 Beijing Games. Both the US Olympic Hall of Fame and the Worldwide Swimming Hall of Fame have induced him.

5. Brooke Moore

Brooke Moore

From the most famous people with Klinefelter Syndrome, this beauty blogger Brooke describes herself as a trans female heterosexual. At the beginning, she was born as a boy, Bradley. She used to be attracted to Barbie dolls as well as Disney princesses, which are popular among young girls. Her body continued to change as she reached adolescence at the young age of 13, developing breasts, not growing facial hair, as well as never breaking in her voice. It was difficult for her to attend an all-boys school because she was frequently teased for being unique. 

She was resolute and strong, though. She went even so far as to start growing her hair and applying several layers of makeup. She modified her name when she was sixteen, and at that point, everybody assumed she was a girl. She didn’t fully comprehend the alterations her body was undergoing until she received a diagnosis in her early 20s. She claims that nothing needs to be corrected, so she is unable to see any need for corrective surgeries. 

6. Lauren Forster

famous people with klinefelter syndrome

This stunner model grew up in South Africa’s Durban area. Once she realized she had been raised with the incorrect gender, she was just 4 years old. Afterwards, Klinefelter syndrome was identified in her. Her family acknowledged her as a girl as well as was really encouraging. People didn’t harass or criticize her since they recognized her as a girl. At the age of 17, she started hormone therapy, as well as a year later, she had gender affirming surgery. 

This sharp-cheeked woman with intense blue eyes rose to prominence as a model as well as conquered the globe. She was referred to as a male in a tabloid article. Despite the fact that this could cripple almost anybody, Forster achieved the strength to accept her gender identity, gained acceptance in her fields, and went on to adorn the glossy covers of the leading fashion brands in the sectors. She also speak out for the LGBTQ community using her platform.

7. Tom Cruise

Tom Cruise

Some of the most well-known and affluent actors in America are Tom Cruise. For his fame, he has won numerous awards. Although there has never been any official confirmation, there have long been rumors that Tom Cruise suffers from Klinefelter syndrome. His bodily characteristics—he is tall, has broad hips, and an elongated body type—his lack of biological paternity for his three kids, and his dyslexia—an additional indication of the symptom—provided the foundation for these assumptions.

8. Renée Richards

famous people with klinefelter syndrome

Renée Richards, a former tennis player and American ophthalmologist, rose to fame after undergoing a sex conversion procedure and competing as a woman in the 1976 US Open. Richards played on the collegiate tour in the 1970s. In college, she began dressing like a woman, that was unprecedented. She eventually took on the French name Renee, meaning “reborn.” In June 1970, Richards tied the knot with model Barbara Mole. The couple had a child named Nicholas in 1972 before divorcing in 1975. She gave up playing tennis in order to focus on her medical career again, moving it to Park Avenue in New York.

9. Lili Elbe

Lili Elbe

She was an openly transgender painter from Denmark who was one of the first to get gender-affirming surgery. She was raised in Vejle, Denmark, in 1982. She painted landscapes. It’s possible that she was born with a mix of male and female traits, but people have said this idea isn’t true. Other stories say she might have had a condition called Klinefelter syndrome. Gerda Gottlieb, her companion, illustrated booKlinefelter Syndrome for fashion magazines and was also a talented artist. When Elbe discovered she liked the stockings as well as heels she wore to cover for Gerda’s girl who was running late for a sitting, she began dressing in women’s attire. 

Lili was chosen as the name on a friend’s recommendation. She underwent a number more operations after her initial procedure in Germany because the procedure was still being tested. After that, she got a legal name change, however her union with Gerda was dissolved. She once wrote an essay in which she bemoaned society’s recognition of only two sexes as well as announced her departure from the art field. After Elbe and Gerda parted ways, she started dating Claude Lejeune, a French art dealer. The last procedure she had was a uterine implant procedure in 1931. Since the procedure was still relatively experimental, her death was caused by serious side effects from it.

10. Janet Mock

famous people with klinefelter syndrome

She went through a gender-reassign process when she was 18 years old; she was born as Charles and is now a well-known American writer as well as TV producer. Her memoir “Redefining Realness” was a bestseller in the New York Times. Her work includes several pieces about transgender people published in Elle, Advocate, as well as People, and also the highly acclaimed LGBTQ series “Pose (2018)” (for which she won a Primetime Emmy) as well as the Netflix series “Hollywood (2020)”. Since she has consistently avoided answering inquiries about her Klinefelter Syndrome in interviews, the diagnosis has remained unconfirmed.

11. Barry Kenneth Cossey 

Barry Kenneth Cossey 

Barry Kenneth Cossey was her assigned male name at birth when she came into the world on August 31, 1954. During the ’70s, ’80s, and ’90s, this towering six-foot model made an appearance. Due to her stunning good look, she was in high demand as a supermodel; she made appearances in Playboy and also had a role in a James Bond film. 

Following the film’s worldwide success, a transgender person’s identity was revealed to the globe through a leaked newspaper. Cossey began hormone treatment promptly after receiving her formal diagnosis of Klinefelter syndrome at the age of seventeen. She saved enough money from her job as a topless stripper in Rome to have sex reassignment surgery.

12. Semenya Caster

Semenya Caster

An Olympic gold champion, Semenya is well-known in her home country of South Africa. The rumors about her Klinefelter syndrome are mostly based on her appearance. The public wasn’t ever informed of her diagnosis, though. Many people think she shouldn’t be able to perform with other women due to her high levels of testosterone, that give her an advantage, and she has experienced criticism, abuse, and invasions of confidentiality over the years. She has had to overcome numerous obstacles, such as taking medicine to suppress her testosterone levels so she could compete as well as passing a medical exam that was disguised as a dope test. They had a child via insemination together with her spouse Violet.

13. Jamie Lee Curtis

Jamie Lee Curtis

Aside from acting, writing, blogging, and campaigning, she is a citizen of the United States. Her acting resume includes roles in films with a combined gross of over $100 million, while she has also been in a number of independent blockbusters. Many people think she was born a boy with Klinefelter syndrome as well as her parents offered her a gender-neutral name to accommodate her transition, even though no one has ever confirmed this. The speculation was fueled by her interviews when she flat-out refused to address the condition.

14. Veronique Francoise Caroline Renald

famous people with klinefelter syndrome

The Dutch author painter, actor is well known worldwide. Panto was her new name following a 2000 meeting with the Dalai Lama at her house in McLeodganj, Dharamsala, India. She became the most youthful person in Dutch history to undergo sexual reassignment in 1982 after being born as a men. At a young age, she received the formal diagnosis of Klinefelter Syndrome. 

Her memories, PHOLOMOLO: No Man, No Woman details her experiences with gender identity and transgender issues. Several of the connections she recounts in her memory came to a conclusion after her illness was made public. She is additionally the brains of Panto Foundation, which helps Tibetan refugees in India by collecting donations. 

15. Richard Branson

Richard Branson

Richard is an entrepreneur, writer, and investor from the United Kingdom. He is also one of the famous people with Klinefelter Syndrome. A number of his ventures, including Virgin Records, Virgin Galactic, Virgin Atlantic, got their existence from him. Although Branson received a childhood diagnosis of Klinefelter Syndrome, It has not ever stood in the way of him realising his ambitions. Being one of the globe’s most Prosperous businessmen, he amassed a fortune entirely by his own efforts. He has been Knighted by the British government. 

What are the Symptoms and Treatment Procedures of Klinefelter Syndrome?

In adolescence and teenage boys the following are the possible indications and symptoms of Klinefelter Syndrome:

  • A reserved attitude
  • Tall build(long legs, short torso, wide hips)
  • Weariness
  • Small and firm testicles
  • Timidity
  • Feeble bones
  • Breast tissue enlargement or Gynecomastia

Several parents are unaware that their kid has Klinefelter Syndrome until they observe delays in puberty, and the syndrome may be difficult to diagnose.

From this blog you must know that many Famous people with Klinefelter Syndrome have gone through several symptoms like rheumatoid arthritis, lupus, as well as Sjogren’s syndrome. In addition, the syndrome has been associated with a higher risk of pulmonary illness, extragonadal tumors of germ cells, bone loss, cancer of the breast, and vein disease. 

Treatment Procedure:

Many of the signs and symptoms of famous people with Klinefelter Syndrome can be alleviated by therapy with testosterone, however the course of treatment ought to start during puberty.


Several famous people with Klinefelter Syndrome frequently have psychological disorders including depression, anxiety, poor social skills, mental retardation as well as impulsiveness, attention-deficit/hyperactivity disorder, also known as (ADHD), and difficulty solving problems. Approximately 10% of males and boys with the syndrome of Klinefelter also suffer from autism syndrome. Additionally, the illness is highly stigmatized, and numerous individuals choose not to disclose their diagnosis, which prevents them from receiving the necessary support.

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